Official Program
REVIGORA BRASIL
Minas Gerais rises as a new bioeconomy, a symbol of hope for Brazilian biodiversity.
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The Program That Transforms Minas Gerais
The IA Institute launches the REVIGORA BRASIL program, embodied in the complex that brings together the National Center for Ecosystem Revitalization and Restoration and the National Center for the Cryopreservation of Brazilian Fauna at Risk of Extinction.
A new phase of green economic development and biotechnology positions Minas Gerais as an international reference in bioeconomy.
Strategic Location
Where We Are
Located near Belo Horizonte, the Revigora Brasil complex occupies a total area of 22,000 m², with a privileged location in the heart of Minas Gerais.
22k m²
Total Area
Of the REVIGORA BRASIL complex
15 min
From AlphaVille
Reference condominium in the region
45 min
From Belo Horizonte
Capital of the state of Minas Gerais
Resilience
Why Minas Gerais?
A state marked by pain rises as a reference point for hope.
The REVIGORA BRASIL Program is an act of resilience, of rebuilding trust in the power of nature and innovation. The choice of Minas Gerais is not symbolic — it is strategic. Trauma is transformed into a driver of transformation.
The initial location for activities related to rewilding, forest preservation with the participation of Indigenous peoples, and bioeconomy activities is the Serra do Espinhaço Biosphere Reserve.
The REVIGORA BRASIL program will include the first biological collection of the Serra do Espinhaço Biosphere, which will play a fundamental role in research and development (R&D) of new medicines, acting as a biodiversity repository that provides genetic, microbiological, and botanical resources for the Biotechnology Hub.
The Serra do Espinhaço is the longest and most continuous mountain range in Brazil, functioning as the most important ecological corridor south of the Amazon region, with about 1,200 km of extension. Recognized by UNESCO, with 3 national parks and 170 cities in Minas Gerais, it connects crucial biomes (Atlantic Forest, Cerrado, and Caatinga) between Minas Gerais and Bahia, making it fundamental to national biodiversity.
PARQUE NACIONAL DA SERRA DO GANDARELA
SEMPRE-VIVAS NATIONAL PARK
SERRA DO CIPÓ NATIONAL PARK
From the Pain of Environmental Disasters to Innovation
Research activities, innovation, and incentives for sustainable economic development, required by Lei nº 13.540/2017 (CFEM), are the path to creating a new biotechnology industry. This industry will ensure new economic activities, sustainable development, and, at the same time, restore the ecosystems of Minas Gerais, especially the Serra do Espinhaço, which are at serious risk.
This industry will ensure new economic activities, sustainable development, and, at the same time, restore the ecosystems of Minas Gerais, which are at serious risk.
The Trauma Becomes Transformation
Minas Gerais stops being remembered only for tragedy and becomes a symbol of regeneration, science, and a green future.
Chapter
The Program
An Alliance for Biodiversity
The IA Instituto de São Paulo, together with the Instituto Physis de Minas Gerais, federal universities, and various organizations, will transform Minas Gerais into a bioeconomy hub and an international benchmark in ecosystem restoration, cellular biotechnology, genetics, and cryopreservation.
Restoration Center
National Center for Ecosystem Restoration and Revitalization
Serra do Espinhaço Biological Collection
A biodiversity repository made up of collections of bacteria, fungi, viruses, helminths, insects, and mollusks, among others; essential for developing medicines and providing genetic, microbiological, and botanical resources for biotechnology innovations
Biocofre Brasil
First National Cryobank for stem cells and germ cells from critically endangered species
Biotechnology Hub
Companies and laboratories focused on cellular biology and animal genetics
The Big Goal
Cryopreserve and revitalize the DNA of more than 300 animals at high risk of extinction in Brazil.
The initial focus is on the 102 mammals threatened and the 148 species of birds in Brazil that are globally threatened with extinction, protecting the irreplaceable genetic heritage of our fauna.
Chapter
Initial Focus
Birds and mammals in population decline and the critical risk of extinction in the Cerrado and Atlantic Forest biomes
1st Group: Birds of Prey
The first revival and cryopreservation group focuses on majestic Brazilian birds of prey, guardians of the skies and indicators of ecosystem health. Each species plays an irreplaceable ecological role.
Gray Eagle
Top predator, essential for balancing the food chain across Brazil's biomes.
King Vulture
The largest vulture in the Americas, vital for decomposition and nutrient recycling in nature.
Pigeon Hawk
A rare bird of the Atlantic Forest, with a population in rapid decline due to habitat loss.
Harpy Eagle
The largest eagle in the Americas, a symbol of strength and biodiversity, threatened by deforestation.
2nd Group: Threatened Mammals
The second revivification and cryopreservation group brings together emblematic mammals from the Cerrado and the Atlantic Forest — charismatic species whose genetic preservation is urgent to ensure the survival of future generations.
Woolly Spider Monkey
The largest primate in the Americas, endemic to the Atlantic Forest, with fewer than 1,000 individuals.
Jaguar
A symbol of Brazilian conservation, surviving in fragments of Atlantic Forest.
Maned Wolf
The largest canid in South America, guardian of the Cerrado and a seed disperser.
Giant Anteater
Vulnerable species, fundamental for controlling insect populations in ecosystems.
Chapter
Objectives
Strategic Objectives
The REVIGORA BRASIL program is built on ambitious objectives that connect science, economics, and environmental preservation.
New Bioeconomy
Sustainable economic development for Minas Gerais.
International Benchmark
Bioeconomy, revitalization, and fauna cryopreservation
Biotechnology Hub
Cell biology, genetics, and ecosystem restoration
Genetic Industry
Creation of an innovative genetics industry
Environmental and Social Impact
Research Bank
Brazil's largest bank of revitalization and ecosystem restoration research, with a focus on soil and vegetation.
REVIGORA BRASIL Complex
National center for revitalization, restoration, and cryopreservation of Brazilian fauna (BIOCOFRE BRASIL).
Genetic Diversity
Preservation of the DNA of endangered animals, ecosystem recovery, and rewilding projects.
Income Generation
New jobs, ecotourism, and opportunities for communities in Minas Gerais.
Chapter
Timeline
1st Year — Research and Planning
The first year focuses on active knowledge gathering, building partnerships, and beginning the first genetic collections.
Database
Active search for research and evidence-based revival solutions — 6 months
Diffusion Strategies
Planning revival and restoration initiatives for Minas — 6 months
Partnerships with Entities
Active search for organizations with source populations of target species from the Atlantic Forest and Cerrado — 6 months
First Collections
Start of cell collection and cryopreservation of the first 4 bird species — 12 months
1st Year — Structuring Plans
At the same time, the first year consolidates the national plans that will scale the program in the following years.
National Diffusion Plan
Development of the scientific diffusion plan for environmental revival research and technologies — 12 months
BIOCOFRE BRAZIL
National plan for cryopreservation and generation of stem cells for the 300 species at risk — 12 months
REVIGORA Complex
Implementation plan for the complex and the National Biotechs Hub of Minas Gerais — 12 months
Subsequent Years — Expansion and Consolidation
1
Digital Platform
National launch of the REVIGORA BRASIL online platform for knowledge, incentives, and outreach.
2
Construction of the Complex
Installation of the first phase with an environmental education center, cryopreservation, and tourism.
3
Tests and Pilots
Start of reviving and biome restoration research in the greater Belo Horizonte area.
4
1st National Symposium
Event in Belo Horizonte–AlphaVille to showcase research and technologies.
Long-Term Consolidation
01
Biotechnology Hub
Installation of laboratories and the first cell biology and genetics companies in the complex.
02
Rewilding
Beginning of biome rewilding tests and pilots in the Belo Horizonte area.
03
300 Species Preserved
Consolidation of BIOCOFRE BRASIL with a focus on birds and mammals from the Cerrado, Atlantic Forest, Amazon, Pantanal, and Pampas.
Chapter
The Complex
Complexo REVIGORA BRASIL
A multifunctional structure that brings together science, education, conservation, and innovation in a single space, designed to be a national and international reference.
Education Center
Environmental restoration, cell biology, genetics, and green tourism
Themed Space
BIOCOFRE BRASIL — Museum of the Future of Brazilian Animals
National Biobank
BIOCOFRE BRASIL — Bank of species at risk of extinction
Conservation Space
Endangered birds of prey
Biotech Hub
Cell biology laboratories of the Complex
Biocofre Brasil — Museum of the Future
The Museum of the Future of Brazilian Animals will be an immersive space where visitors can learn about the biobank, observe cells under microscopes, and experience multimedia installations about revitalization and genetic editing.
Visitors will learn about NANOTUBES — technology that is revolutionizing cell cryopreservation — through interactive presentations and unique sensory experiences.
An Immersive Experience
The museum will combine cutting-edge science with engaging design to educate and inspire visitors of all ages.
Cryobank Prototype
Visualization of Brazil's 300 most endangered species
Cell Microscopy
Real observation of preserved animal cells
Integrated Multimedia
Immersive installations about gene editing and NANOTUBES
Chapter
Biotechnology Hub
The Biotechnology Hub of Minas Gerais
With 1,200 m² dedicated, the Hub will host high-tech companies focused on generating patents and licensing in animal reproduction cell biology.
Hub Technologies
The goal is to transform Minas Gerais into an international reference in technologies for research, development, and production of innovative products and services in animal cell biology.
Genetic Sequencing
Complete genome mapping of endangered species
Cell Therapies
Generation of stem and germ cells for assisted reproduction
Cloning and Rewilding
Technologies to address extinction challenges and animal protein production
Advanced Cryopreservation
New technologies for commercial and wild species
Chapter
Technological Differentiator
Partnerships with Federal Universities
The major partners are the Brazilian federal universities, which join the program with scientists and technical teams through funding agreements with state research foundations.
The program encourages and supports national technologies for cryopreservation and reproductive genetics, valuing Brazilian scientific knowledge as a driver of innovation.
Carbon Nanotubes
The innovative technology of Carbon Nanotubes enables the precise delivery of genetic material, RNA, and chromosomes inside germ cells — a breakthrough in cryopreservation and species rescue.
How Nanotubes Save Species
CNTs function as non-viral vectors for delivering genetic material, including plasmid DNA and RNA, in a safe and efficient way.
Chemical functionalization of CNTs optimizes delivery efficiency and interaction with the immune system, allowing automatic needles to insert genetic material directly into germ cells.
DOX-SPRB-siRNA
An advanced system that uses nanotubes to deliver genetic complexes to the cell nucleus, enabling precise genetic editing to save species at risk of extinction.
Chapter
Business Plan
Program Sustainability
The IA Instituto is the main proponent and catalyst, working as a co-author and business and investor magnet to accelerate the state's bioeconomy.
1
Solve Environmental Problems
Restoration of damaged ecosystems
2
Generate Bioeconomy
New biotechnology and tourism industry
3
Create BIOCOFRE
First cryobank in South America
Funding Sources
The socio-economic sustainability plan provides multiple funding sources to ensure the program's longevity and impact.
Public Investment
Funds from national programs, parliamentary amendments, and the mandatory 20% from CFEM
International Funds
Funds from environmental reparations and global biodiversity funds
Donations
Fundraising through Law 13.019/2014 and other funding sources
Private Investment
Active fundraising from investors in Brazil and abroad for pet cloning startups, horses, cattle, and award-winning breeding stock
Revigora Brasil
From a state marked by tragedy comes the largest initiative for bioeconomy and genetic preservation of Brazilian fauna.
The future of Brazilian biodiversity starts here. Join this transformation.